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Cleavable Peptide Linkers


Peptide linkers are a class of protease cleavable linkers. Peptide linkers are key components of antibody drug conjugates (ADCs) due to their superior plasma stability and controlled load release mechanism. Well-designed linkers help antibodies selectively deliver cytotoxic drugs to tumor cells and deliver drugs accurately at tumor sites. By introducing PEG into the linker, it increases the water solubility of the linker itself and helps fine-tune the drug DMPK.

DBCO-C4-Val-Cit-PABC-PNP

Catalog: CDAX095

MW: 859.94

$2480

Val-Cit-PAB-OH

Catalog: CDAX007

MW: 379.46

$1200

Val-Cit-alcohol

Catalog: CDAX008

MW: 274.32

$680

Val-Ala-PAB

Catalog: CDAX009

MW: 293.37

$1680

TCO-PEG1-Val-Cit-PABC-PNP

Catalog: CDAX013

MW: 811.89

$1800

TCO-PEG1-Val-Cit-PABC-OH

Catalog: CDAX014

MW: 646.79

$1580

TCO-PEG1-Val-Cit-OH

Catalog: CDAX015

MW: 541.65

$980

SPDP-Val-Cit-PAB-PNP

Catalog: CDAX018

MW: 741.84

$795

SPDP-Val-Cit-PAB-OH

Catalog: CDAX019

MW: 576.73

$750

MC-Val-Cit-PAB-PNP

Catalog: CDAX042

MW: 737.8

$920

MC-Val-Cit-PAB-OH

Catalog: CDAX043

MW: 572.7

$1800

MC-Val-Cit-OH

Catalog: CDAX044

MW: 467.52

$1380

Mc-Val-Ala-PAB-PNP

Catalog: CDAX045

MW: 651.67

$1200

Mc-Val-Ala-PAB

Catalog: CDAX046

MW: 486.57

$1400

MC-Ala-Ala-Asn(Trt)-OH

Catalog: CDAX047

MW: 709.79

$1080

MC(C2)-Val-Cit-PAB-OH

Catalog: CDAX048

MW: 530.58

$1200

MC (C5)-Val-Cit

Catalog: CDAX049

MW: 452.51

$850

Mal-PEG4-Val-Cit-PAB-PNP

Catalog: CDAX050

MW: 871.9

$1400

Mal-PEG4-Val-Cit-PAB-OH

Catalog: CDAX051

MW: 706.8

$1080

Mal-PEG2-Val-Cit-PAB-OH

Catalog: CDAX052

MW: 618.7

$920
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