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DC-Cholesterol Liposomes for DNA/RNA Delivery


DC-cholesterol liposomes are a type of lipid nanoparticle that have shown promise for DNA/RNA delivery. These liposomes are composed of a mixture of cationic and neutral lipids, including 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP), cholesterol, and other components. The cationic lipids in the liposomes interact with the negatively charged DNA or RNA molecules, forming liposome-DNA/RNA complexes that can enter cells and deliver the genetic material. DC-cholesterol liposomes have several advantages for DNA/RNA delivery. They are relatively easy to prepare, can protect the genetic material from degradation, and can be targeted to specific cell types using ligands on the surface of the liposomes. In addition, they are generally well-tolerated by cells and have low toxicity.

CD Bioparticles manufactures and supplies DC-cholesterol liposomes for DNA/RNA delivery research. Contact us to find out how DC-cholesterol liposomes can help your work.

Product Name Catalog Lipid composition Liposome Size Price
Clipos™ Cationic DC-Cholesterol Liposomes CDEGEN-1713 DC-Cholesterol/DOPE (1/1 molar ratio) 100 nm $1680
Clipos™ Cationic DC-Cholesterol Liposomes CDL5002V DOTAP/DC-Cholesterol (50/50 molar ratio) 70-100 nm (by DSL) $1400
Clipos™ Cationic DC-Cholesterol Liposomes CDEGEN-1714 DC-Cholesterol/DOPE (1/2 molar ratio) 100 nm $1680
Clipos™ Cationic DC-Cholesterol Liposomes CDL5003 DC-Cholesterol/DOPE (30/70 molar ratio) 90- 110 nm (by DSL) $795
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