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SPDP-Val-Cit-PAB-PNP


SPDP-Val-Cit-PAB-PNP

Catalog:CDAX018

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$795

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Common UseSPDP-Val-Cit-PAB-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure SPDP-Val-Cit-PAB-PNP
Purity≥95%
Molecular Weight741.84
Molecular FormulaC33H39N7O9S2
CAS No.159857-81-5
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