Common Use | MC (C5)-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group. |
Structure | |
Purity | ≥95% |
Molecular Weight | 452.51 |
Molecular Formula | C20H32N6O6 |
CAS No. | 870487-10-8 |
Catalog: CDAX100
Catalog: CDAX109
Catalog: CDAX068
Catalog: CDAX064
Catalog: CDAX065
Catalog: CDAX106
Catalog: CDAX014
Catalog: CDAX045
1. Download the template.
2. Enter product information on the template (maximum number of products: 200).
3. Load the file using selector below.
1. Download the template.
2. Enter product information on the template (maximum number of products: 200).
3. Load the file using selector below.