Common Use | MC (C5)-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group. |
Structure | |
Purity | ≥95% |
Molecular Weight | 452.51 |
Molecular Formula | C20H32N6O6 |
CAS No. | 870487-10-8 |
Catalog: CDAX091
Catalog: CDAX013
Catalog: CDAX112
Catalog: CDAX073
Catalog: CDAX113
Catalog: CDAX047
Catalog: CDAX108
Catalog: CDAX064
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