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Mal-PEG1-Val-Cit-PABC-PNP


Mal-PEG1-Val-Cit-PABC-PNP

Catalog:CDAX053

Unit Size
Price
$1800

Buy Now Datasheet

Common UseMal-PEG1-Val-Cit-PABC-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Mal-PEG1-Val-Cit-PABC-PNP
Purity≥95%
Molecular Weight739.74
Molecular FormulaC34H41N7O12
CAS No.2249935-92-8

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