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Fmoc-Val-Cit-PAB-PNP


Fmoc-Val-Cit-PAB-PNP

Catalog:CDAX061

Unit Size
Price
$720

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Common UseFmoc-Val-Cit-PAB-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Fmoc-Val-Cit-PAB-PNP
Purity≥95%
Molecular Weight766.8
Molecular FormulaC40H42N6O10
CAS No.863971-53-3
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