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Fmoc-Val-Cit-PAB


Fmoc-Val-Cit-PAB

Catalog:CDAX062

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$550

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Common UseFmoc-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Fmoc-Val-Cit-PAB
Purity≥95%
Molecular Weight601.7
Molecular FormulaC33H39N5O6
CAS No.159858-22-7
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