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exo-BCN-Val-Cit-PAB-PNP


exo-BCN-Val-Cit-PAB-PNP

Catalog:CDAX075

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$1280

Buy Now Datasheet

Common Useexo-BCN-Val-Cit-PAB-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure exo-BCN-Val-Cit-PAB-PNP
Purity≥95%
Molecular Weight720.77
Molecular FormulaC36H44N6O10
CAS No.2151085-14-0

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