Common Use | DBCO-PEG4-Propionic-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group. |
Structure | |
Purity | ≥95% |
Molecular Weight | 870.02 |
Molecular Formula | C46H59N7O10 |
Catalog: CDAX061
Catalog: CDAX053
Catalog: CDAX094
Catalog: CDAX046
Catalog: CDAX097
Catalog: CDAX117
Catalog: CDAX009
Catalog: CDAX098
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