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DBCO-C4-Val-Cit-PABC-PNP


DBCO-C4-Val-Cit-PABC-PNP

Catalog:CDAX095

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Price
$2480

Buy Now Datasheet

Common UseDBCO-C4-Val-Cit-PABC-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure DBCO-C4-Val-Cit-PABC-PNP
Purity≥95%
Molecular Weight859.94
Molecular FormulaC46H49N7O10

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