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Boc-Val-Cit-PAB-PNP


Boc-Val-Cit-PAB-PNP

Catalog:CDAX096

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$620

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Common UseBoc-Val-Cit-PAB-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Boc-Val-Cit-PAB-PNP
Purity≥95%
Molecular Weight644.67
Molecular FormulaC30H40N6O10
CAS No.870487-10-8
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