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Azido-PEG4-Val-Cit-PAB-OH


Azido-PEG4-Val-Cit-PAB-OH

Catalog:CDAX111

Unit Size
Price
$850

Buy Now Datasheet

Common UseAzido-PEG4-Val-Cit-PAB-OH-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Azido-PEG4-Val-Cit-PAB-OH
Purity≥95%
Molecular Weight652.75
Molecular FormulaC29H48N8O9
CAS No.2055024-64-9

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