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Azido-PEG3-Val-Cit-PAB-PNP


Azido-PEG3-Val-Cit-PAB-PNP

Catalog:CDAX112

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$1580

Buy Now Datasheet

Common UseAzido-PEG3-Val-Cit-PAB-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Azido-PEG3-Val-Cit-PAB-PNP
Purity≥95%
Molecular Weight773.8
Molecular FormulaC34H47N9O12
CAS No.2055047-18-0

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