Azido-PEG1-Val-Cit-PABC-OH


Azido-PEG1-Val-Cit-PABC-OH

Catalog:CDAX116

Unit Size:100 mg, 250 mg

INQUIRY Datasheet

Common Use Azido-PEG1-Val-Cit-PABC-OH-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Azido-PEG1-Val-Cit-PABC-OH
Molecular Weight 520.59
Purity ≥95%
Molecular Formula C23H36N8O6
CAS No. 2055041-40-0

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