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Clipos™ DT-061 (SMAP) Encapsulated Liposomes


Catalog:CDEPG-02

Unit Size
Price
$2200

Buy Now Need technical support? Datasheet

Storage2 °C to 8 °C (do not freeze)
DescriptionPEGylated liposomes containing PP2A activator DT-061 (SMAP). DT-061 is an activator of protein phosphatase 2A (PP2A). PP2A regulates many cellular signaling pathways including MAPK/ERK, Wnt/β-catenin, Akt/mTOR, GSK3β, p53/apoptosis, cell cycle, and others. This product can be used in vitro or in vivo for studying the effects of PP2A activation and could be applied to preclinical therapy of KRAS-mutant and MYC-driven tumors. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.
Lipid compositionPEGylated liposomes
Liposome Size70-120 nm
Lipid Molar Concentration60 mM
Shelf-lifeAt least 1 month
Encapsulated DrugDT-061
Drug concentration4.0 mg/mL
Inside Buffer300 mM sucrose
Outside Buffer300 mM sucrose
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