Common Use | Poly-L-lysine hydrobromide is a positively charged synthetic polyamino acid having one HBr per lysine unit. It is a crystalline solid soluble in water. Applications for poly-L-lysine hydrobromide include the promotion of cell adhesion to solid substrates for culture dishes or slides, the conjugation to active molecules for improved activities, the layer-by-layer deposition techniques, and the complexation with nucleic acids for gene expression. For cell culture applications, poly-L-lysine hydrobromide with a molecular weight greater than 30,000 Da is recommended. The poly-L-lysine hydrobromide (MW=52,000 Da) is easier to use because it is less viscous in solution; however, the poly-L-lysine hydrobromide with an higher molecular weight (MW=84,000 Da) has more attachement sites per polymer chain available to the cells. Our poly-L-lysine hydrobromide has been purified by dialysis, sterile-filtered on 0.2um, lyophilized, and stored under Ar. |
Structure | |
Storage | Store poly-L-lysine hydrobromide under the condition of flushing with argon and protecting from light, and below -15°C. |
CAS No. | 25988-63-0 |
PLL Molecular Weight | 2100 Da |
Number of Repeating Units | 10 PLL HBr |
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