Common Use | SI-109 is a potent STAT3 SH2 domain inhibitor (Ki=9 nM) with antitumor activity. SI-109 effectively inhibits the transcriptional activity of STAT3 (IC50=3 μM). SI-109 and an analog of CRBN ligand lenalidomide have been used to design PROTAC STAT3 degrader SD-36. |
Structure | |
Purity | 0.9948 |
Storage | • Stored under nitrogen, -20°C • In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Molecular Weight | 835.79 |
Molecular Formula | C40H44F2N7O9P |
CAS No. | 2429877-30-3 |
Appearance | Solid |
Solubility | DMSO: 100 mg/mL (210.28 mM) |
Catalog: CDMDC31
Catalog: CDMDC24
Catalog: CDMDC53
Catalog: CDMDC18
Catalog: CDMDC13
Catalog: CDMDC01
Catalog: CDMDC11
Catalog: CDMDC25
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