SI-109


SI-109

Catalog:CDMDC04

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INQUIRY Datasheet

Common Use SI-109 is a potent STAT3 SH2 domain inhibitor (Ki=9 nM) with antitumor activity. SI-109 effectively inhibits the transcriptional activity of STAT3 (IC50=3 μM). SI-109 and an analog of CRBN ligand lenalidomide have been used to design PROTAC STAT3 degrader SD-36.
Structure SI-109
Molecular Weight 835.79
Purity 0.9948
Molecular Formula C40H44F2N7O9P
CAS No. 2429877-30-3
Appearance Solid
Storage • Stored under nitrogen, -20°C
• In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solubility DMSO: 100 mg/mL (210.28 mM)

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