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SI-109


SI-109

Catalog:CDMDC04

INQUIRY Datasheet

Common UseSI-109 is a potent STAT3 SH2 domain inhibitor (Ki=9 nM) with antitumor activity. SI-109 effectively inhibits the transcriptional activity of STAT3 (IC50=3 μM). SI-109 and an analog of CRBN ligand lenalidomide have been used to design PROTAC STAT3 degrader SD-36.
Structure SI-109
Purity0.9948
Storage• Stored under nitrogen, -20°C • In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Molecular Weight835.79
Molecular FormulaC40H44F2N7O9P
CAS No.2429877-30-3
AppearanceSolid
SolubilityDMSO: 100 mg/mL (210.28 mM)
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