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Abemaciclib metabolite M18 hydrochloride


Abemaciclib metabolite M18 hydrochloride

Catalog:CDMDC12

INQUIRY Datasheet

SynonymLSN3106729 hydrochloride
Common UseAbemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib, is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader.
Structure Abemaciclib metabolite M18 hydrochloride
Purity0.9801
Storage• 4°C, sealed storage, away from moisture • In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Molecular Weight531
Molecular FormulaC25H29ClF2N8O
AppearanceSolid
Solubility• DMSO: ≥ 125 mg/mL (235.4 mM) • H2O: ≥ 100 mg/mL (188.32 mM)
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