Common Use | Androgen receptor antagonist 1 is an orally available full androgen receptor (AR) antagonist with an IC50 of 59 nM. Androgen receptor antagonist 1 (Compound 6) can be used in the synthesis of PROTAC AR degraders, which results 24% and 47 % AR protein degradation in LNCaP cells at 1 μM and 10 μM, respectively. |
Structure | |
Purity | 0.9939 |
Storage | • Powder: -20°C 3 years; 4°C 2 years • In solvent: -80°C 6 months; -20°C 2 month |
Molecular Weight | 416.9 |
Molecular Formula | C21H25ClN4O3 |
CAS No. | 1338812-36-4 |
Appearance | Solid |
Solubility | DMSO: 100 mg/mL (239.87 mM) |
Catalog: CDMDC09
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Catalog: CDMDC15
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