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Androgen receptor antagonist 1


Androgen receptor antagonist 1

Catalog:CDMDC26

INQUIRY Datasheet

Common UseAndrogen receptor antagonist 1 is an orally available full androgen receptor (AR) antagonist with an IC50 of 59 nM. Androgen receptor antagonist 1 (Compound 6) can be used in the synthesis of PROTAC AR degraders, which results 24% and 47 % AR protein degradation in LNCaP cells at 1 μM and 10 μM, respectively.
Structure Androgen receptor antagonist 1
Purity0.9939
Storage• Powder: -20°C 3 years; 4°C 2 years • In solvent: -80°C 6 months; -20°C 2 month
Molecular Weight416.9
Molecular FormulaC21H25ClN4O3
CAS No.1338812-36-4
AppearanceSolid
SolubilityDMSO: 100 mg/mL (239.87 mM)
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