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Desmethyl-QCA276


Desmethyl-QCA276

Catalog:CDMDC38

INQUIRY Datasheet

SynonymPROTAC BRD4-binding moiety 4
Common UseDesmethyl-QCA276 (PROTAC BRD4-binding moiety 4), the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM.
Structure Desmethyl-QCA276
Molecular Weight387.46
Molecular FormulaC21H17N5OS
CAS No.2126819-55-2
AppearanceSolid

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