Desmethyl-QCA276


Desmethyl-QCA276

Desmethyl-QCA276

Catalog:CDMDC38

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INQUIRY Datasheet

Synonym PROTAC BRD4-binding moiety 4
Common Use Desmethyl-QCA276 (PROTAC BRD4-binding moiety 4), the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM.
Structure Desmethyl-QCA276
Molecular Weight 387.46
Molecular Formula C21H17N5OS
CAS No. 2126819-55-2
Appearance Solid

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