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SirReal1-O-propargyl


SirReal1-O-propargyl

Catalog:CDMDC40

INQUIRY Datasheet

SynonymPROTAC Sirt2-binding moiety 1
Common UseSirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2.
Structure SirReal1-O-propargyl
Storage• 4°C, stored under nitrogen • In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Molecular Weight424.54
Molecular FormulaC21H20N4O2S2
CAS No.1862237-99-7
AppearanceSolid
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