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Poly(ε-caprolactone)-Hydrazone(hyd)- Poly(ethylene glycol)-Thiol


Poly(ε-caprolactone)-Hydrazone(hyd)- Poly(ethylene glycol)-Thiol

PCL-Hyd-PEG-Thiol(SH)

Catalog:PHRC463

Unit Size
Price
$1170

Buy Now Need technical support? Datasheet

Common UseHydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-Thiol was coupled to form micelles with pH response. pH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells
Structure Poly(ε-caprolactone)-Hydrazone(hyd)- Poly(ethylene glycol)-Thiol
PEG Molecular Weight750 Da, 1000 Da, 2000 Da, 3400 Da, 5000 Da, 10000 Da
Functional GroupThiol
PCL Molecular WeightAs your request
Storage-20 °C, protected from light and moisture
AppearanceWhite powder/viscous liquid
Stability1 year
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