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Doxorubicin-Hydrazone-Polyethylene glycol-Amine


Doxorubicin-Hydrazone-Polyethylene glycol-Amine

DOX-Hyd-PEG-NH2

Catalog:PHRC475

Unit Size
Price
$1950

Buy Now Need technical support? Datasheet

Common UseThe hydrazone bond is stable in the weak alkali condition, but it can break quickly in the weak acid condition, thus releasing the drug.PEG-DOX, a prodrug of doxorubicin, has multiple advantages: it greatly increases the water solubility of doxorubicin. Moreover, PEG-DOX, a prodrug of doxorubicin, can effectively self assemble to form stable nanoparticles in physiological environment, and the EPR effect of nanodrugs can be used for targeted drug delivery
Structure Doxorubicin-Hydrazone-Polyethylene glycol-Amine
PEG Molecular Weight1000 Da
Functional GroupAmine
Purity>95%
Storage-20 °C, protected from light and moisture
AppearanceBrown/off-white solid or viscous liquid
Stability1 year
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