Doxorubicin-Hydrazone-Polyethylene glycol-Amine
DOX-Hyd-PEG-NH2
Catalog:PHRC475
Common Use | The hydrazone bond is stable in the weak alkali condition, but it can break quickly in the weak acid condition, thus releasing the drug.PEG-DOX, a prodrug of doxorubicin, has multiple advantages: it greatly increases the water solubility of doxorubicin. Moreover, PEG-DOX, a prodrug of doxorubicin, can effectively self assemble to form stable nanoparticles in physiological environment, and the EPR effect of nanodrugs can be used for targeted drug delivery |
Structure |
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PEG Molecular Weight | 1000 Da |
Functional Group | Amine |
Purity | >95% |
Storage | -20 °C, protected from light and moisture |
Appearance | Brown/off-white solid or viscous liquid |
Stability | 1 year |
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