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YGRKKRRQRRRKLSSIESDV (TFA salt)


YGRKKRRQRRRKLSSIESDV (TFA salt)

Tat-NR2B9c TFA

Catalog:CDCCP23-011L

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$450

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SynonymTat-NR2Bct TFA, NA-1 TFA
Common UseTat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c TFA disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c TFA also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy
Structure YGRKKRRQRRRKLSSIESDV (TFA salt)
Purity≥99%
StoragePowder: -80 °C, 2 years; -20 °C, 1 year. In solvent: -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)
Molecular Weight2632.9
Molecular FormulaC105H188N42O30.C2HF3O2
CAS No.1834571-04-8
AppearanceSolid
SolubilitySoluble in water
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