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YGRKKRRQRRRKLSSIESDV


YGRKKRRQRRRKLSSIESDV

Tat-NR2B9c

Catalog:CDCCP23-019L

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$450

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SynonymTat-NR2Bct, NA-1
Common UseTat-NR2B9c (Tat-NR2Bct; NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy
Structure YGRKKRRQRRRKLSSIESDV
Purity≥99%
StoragePowder: -80 °C, 2 years; -20 °C, 1 year. In solvent: -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)
Molecular Weight2518.88
Molecular FormulaC105H188N42O30
CAS No.500992-11-0
AppearanceSolid
SolubilitySoluble in water
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