Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-Amine


Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-Amine

NH2-PLGA-PEG-MAL

Catalog:CDN796

Unit Size:100 mg

INQUIRY Datasheet

Synonym Mal-PEG-PLGA-NH2
Common Use Maleimide-PEG-Poly(lactide-co-glycolide)-Amine is a functional amphiphilic block copolymer with maleimide capped PEG and amine capped PLGA. Mal-PEG-PLGA-NH2 can self assemble into micelles/nanoparticles. Maleimide on the micelle surface can conjugate with thiol, SH, sulfhydryl or mercapto group to form a disulfide bond. Amine group on the PLGA block can be used for drug conjugation or micellar core modification.  Hydrophobic drugs is encapsulated in the PLGA core for targeted drug delivery.
Structure Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-Amine
PLGA Molecular Weight 5,000 Da
PEG Molecular Weight 1,000 Da
Monomer Ratio LA:GA 50:50
Functional Group Amine/Maleimide

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