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Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-Amine


Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-Amine

NH2-PLGA-PEG-MAL

Catalog:CDN796

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$850

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SynonymMal-PEG-PLGA-NH2
Common UseMaleimide-PEG-Poly(lactide-co-glycolide)-Amine is a functional amphiphilic block copolymer with maleimide capped PEG and amine capped PLGA. Mal-PEG-PLGA-NH2 can self assemble into micelles/nanoparticles. Maleimide on the micelle surface can conjugate with thiol, SH, sulfhydryl or mercapto group to form a disulfide bond. Amine group on the PLGA block can be used for drug conjugation or micellar core modification.  Hydrophobic drugs is encapsulated in the PLGA core for targeted drug delivery.
Structure Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-Amine
PEG Molecular Weight1,000 Da
Functional GroupAmine/Maleimide
PLGA Molecular Weight5,000 Da
Monomer RatioLA:GA 50:50
Polymer TypesPLGA
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