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Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-COOH


Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-COOH

COOH-PLGA-PEG-MAL

Catalog:CDN805

Unit Size
Price
$850

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Common UseMaleimide-PEG-Poly(lactide-co-glycolide)-COOH is a functional amphiphilic block copolymer with maleimide capped PEG and amine capped PLGA. Mal-PEG-PLGA-NH2 can self assemble into micelles/nanoparticles. Maleimide on the micelle surface can conjugate with thiol, SH, sulfhydryl or mercapto group to form a disulfide bond. COOH group on the PLGA block can be used for drug conjugation or micellar core modification.  Hydrophobic drugs is encapsulated in the PLGA core for targeted drug delivery.
Structure Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-COOH
PEG Molecular Weight1,000 Da
Functional GroupCOOH/Maleimide
PLGA Molecular Weight5,000 Da
Monomer RatioLA:GA 50:50
Polymer TypesPLGA
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