Maleimide-Poly(ethylene glycol)-Poly(lactide-co-glycolide)-COOH
COOH-PLGA-PEG-MAL
Catalog:CDN811
Common Use | Maleimide-PEG-Poly(lactide-co-glycolide)-COOH is a functional amphiphilic block copolymer with maleimide capped PEG and amine capped PLGA. Mal-PEG-PLGA-NH8 can self assemble into micelles/nanoparticles. Maleimide on the micelle surface can conjugate withhiol, SH, sulfhydryl or mercapto group to form a disulfide bond. COOH group on the PLGA block can be used for drug conjugation or micellar core modification. Hydrophobic drugs is encapsulated in the PLGA core for targeted drug delivery. |
Structure | |
PEG Molecular Weight | 1,000 Da |
Functional Group | COOH/Maleimide |
PLGA Molecular Weight | 20,000 Da |
Monomer Ratio | LA:GA 50:50 |
Polymer Types | PLGA |
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