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Licochalcone B


Licochalcone B

Catalog:CDPE23-018-L

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$495

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Common UseLicochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction
Structure Licochalcone B
Purity≥99%
Storage4 °C, protect from light. In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light)
Molecular Weight286.28
Molecular FormulaC16H14O5
CAS No.58749-23-8
AppearanceSolid
SolubilitySoluble in DMSO
InsolubleInsoluble in H2O
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