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7,4'-Dihydroxyflavone


7,4'-Dihydroxyflavone

7,4'-DHF

Catalog:CDPE23-019-L

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Price
$450

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Common Use7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM
Structure 7,4'-Dihydroxyflavone
Purity≥99%
StoragePowder: -20 °C, 3 years; 4 °C, 2 year. In solvent: -80 °C, 2 years; -20 °C, 1 year
Molecular Weight254.24
Molecular FormulaC15H10O4
CAS No.2196-14-7
AppearanceSolid
SolubilitySoluble in DMSO
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