Keywords Search Google Search

0Quotes

0Cart

Clipos™ CXCR1 mRNA Lipid Nanoparticles

Catalog:CDL23-086-L

Unit Size

200 μL

Price: $1695

Buy Now Need technical support? Datasheet

Specifications QA & Reviews

Storage	Store at 4°C
Description	CXCR1 (C-X-C motif chemokine receptor 1), also known as CD181, is a member of the G protein-coupled receptor family and is encoded by the CXCR1 gene. CXCR1 is expressed on neutrophils, monocytes, macrophages, basophils, natural killer T cells, and interacts with high affinity with the primary ligand CXCL8 (interleukin 8 or IL8). By binding to IL8, CXCR1 transduces signals through a G protein-activated second messenger system, leading to neutrophil chemotaxis and activation. CXCR1 has also been shown to play an important role in the regulation of neuronal apoptosis. CXCR1 was found to be expressed on the cell surface of white blood cells and tumor cells, and this expression was independent of cancer stage. In this way, it has been identified as a potential therapeutic target. This product is designed as a tool for the delivery and expression of CXCR1 mRNA for research. The product leverages the lipid nanoparticle (LNP) technology platform for simple and efficient delivery of CXCR1 mRNA to a variety of mammalian cells in vitro and in vivo. The LNPs used are formulated with SM-102, DSPC, cholesterol and DMG-PEG2000 at an optimal molar concentration for a high rate of encapsulation and efficient mRNA delivery. CXCR1 protein is approximately 39 kD, consisting of 350 amino acids
Lipid composition	SM-102/DSPC/Cholesterol/DMG-PEG2000
Technical Notes	Work with mRNA-LNP on ice. It is important to minimize the time that the product spends at room temperature; after handling product during experiments, return immediately to ice.Upon receiving product, briefly pulse spin before opening to ensure product is at bottom of container; it is important not to spin for too long as this may rupture mRNA-LNP’s. Do not vortex. mRNA-LNP products should only be handled with certified RNAase-free reagents and consumables; use of filtered pipette tips is highly recommended
Encoding mRNA	CXCR1
In Vitro QC (Cell Types)	HEK293S
Technology Applications	Protein research

Related Products

Product Name	Catalog	Lipid composition	Liposome Size	Price
Clipos™ CXCR1 mRNA Lipid Nanoparticles	CDL23-065-L	SM-102/DSPC/Cholesterol/DMG-PEG2000		$1980
Clipos™ CXCR1 mRNA Lipid Nanoparticles	CDL23-082-L	SM-102/DSPC/Cholesterol/DMG-PEG2000		$1695
Clipos™ CXCR1 mRNA Lipid Nanoparticles	CDL23-052-L	SM-102/DSPC/Cholesterol/DMG-PEG2000		$1695
Clipos™ CXCR1 mRNA Lipid Nanoparticles	CDL23-016-L	SM-102/DSPC/Cholesterol/DMG-PEG2000		$1695
Clipos™ CXCR1 mRNA Lipid Nanoparticles	CDL23-042-L	SM-102/DSPC/Cholesterol/DMG-PEG2000		$1595
Clipos™ CXCR1 mRNA Lipid Nanoparticles	CDL23-096-L	SM-102/DSPC/Cholesterol/DMG-PEG2000		$1328
Clipos™ CXCR1 mRNA Lipid Nanoparticles	CDPM11	SM-102/DSPC/cholesterol/DMG-PEG2000		INQUIRY
Clipos™ CXCR1 mRNA Lipid Nanoparticles	CDMB03			INQUIRY

Products

Fill out the form below
to receive a quote

Services

Drug Targeting Strategy

Drug Delivery Nanoparticles Formulation

Bioparticles Analysis and Characterization

Bioactive Particles & Fillers Production

Functional Biomedical Coatings

Lipid Library Development for Drug Delivery

Aptamer Targeted Drug Delivery System

Other Types of Drug Delivery

Products

Liposome System

Chelating Agents

Bioactive Matrixes

Porous Organic Materials

Biopolymers & Synthetic Polymers

Exosome Products

Cleavable Linkers

Pharmaceutical Excipients (drug/medical grade)

Tissue Engineering Scaffold

(USA)
(Europe)

Cookie Policy | Privacy Policy | Copyright © CD Bioparticles. All rights reserved.

×

Upload products to cart

1. Download the template.

2. Enter product information on the template (maximum number of products: 200).

3. Load the file using selector below.

×

Upload products to quote list

1. Download the template.

2. Enter product information on the template (maximum number of products: 200).

3. Load the file using selector below.