×
Shopping Cart
×
Quote List

Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles


Catalog:CDL23-087-L

Unit Size
Price
$1595

Buy Now Need technical support? Datasheet

StorageStore at 4°C
DescriptionHepatitis B virus (HBV) is a partially double-stranded DNA virus, a member of the Hepadnavirus family, which causes the disease hepatitis B. The virus particle consists of an outer lipid envelope and an icosahedral nucleocapsid core composed of protein. The nucleocapsid encloses the viral DNA and a DNA polymerase that has reverse transcriptase activity similar to retroviruses. The outer envelope contains embedded proteins which are involved in viral binding of, and entry into, susceptible cells. This product is designed as a tool for the delivery and expression of anti-HBV CAR mRNA for research. The product leverages the lipid nanoparticle (LNP) technology platform for simple and efficient delivery of anti-HBV CAR mRNA to a variety of mammalian cells in vitro and in vivo. The LNPs used are formulated with SM-102, DSPC, cholesterol and DMG-PEG2000 at an optimal molar concentration for a high rate of encapsulation and efficient mRNA delivery. The anti-HBV CAR fusion protein in this product is approximately 58 kD and consists of anti-HBV scFv (single-chain variable fragment) linked to a second-generation CAR (chimeric antigen receptor) containing the CD8 hinge and transmembrane domain and 4-1BB and CD3ζ signaling domains. The full-length amino acid sequence of this anti-HBV CAR fusion protein is available upon request
Lipid compositionSM-102/DSPC/Cholesterol/DMG-PEG2000
Technical NotesWork with mRNA-LNP on ice. It is important to minimize the time that the product spends at room temperature; after handling product during experiments, return immediately to ice.Upon receiving product, briefly pulse spin before opening to ensure product is at bottom of container; it is important not to spin for too long as this may rupture mRNA-LNP’s. Do not vortex. mRNA-LNP products should only be handled with certified RNAase-free reagents and consumables; use of filtered pipette tips is highly recommended
Encoding mRNAAnti-HBV CAR
In Vitro QC (Cell Types)HEK293S
Technology ApplicationsCAR-T
My Review for Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles

Required fields are marked with *

Overall Rating *
×
Related Products
Product Name Catalog Lipid composition Liposome Size Price
Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles CDL23-030-L SM-102/DSPC/Cholesterol/DMG-PEG2000 $1980
Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles CDL23-060-L SM-102/DSPC/Cholesterol/DMG-PEG2000 $1595
Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles CDL23-031-L SM-102/DSPC/Cholesterol/DMG-PEG2000 $1980
Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles CDPM14 SM-102/DSPC/cholesterol/DMG-PEG2000 INQUIRY
Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles CDL23-071-L SM-102/DSPC/Cholesterol/DMG-PEG2000 $1595
Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles CDL23-061-L SM-102/DSPC/Cholesterol/DMG-PEG2000 $1595
Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles CDL23-052-L SM-102/DSPC/Cholesterol/DMG-PEG2000 $1695
Clipos™ Anti-HBV CAR mRNA Lipid Nanoparticles CDL23-062-L SM-102/DSPC/Cholesterol/DMG-PEG2000 $1595
Products
Fill out the form below
to receive a quote

GET A QUOTE

Cookie Policy | Privacy Policy | Copyright © CD Bioparticles. All rights reserved.
×
Upload products to cart

1. Download the template.

2. Enter product information on the template (maximum number of products: 200).

3. Load the file using selector below.

Drag and drop your file here or

Choose file
*.xlsx (max 20 MB)

4. Click the "Add to cart" button.

×
Upload products to quote list

1. Download the template.

2. Enter product information on the template (maximum number of products: 200).

3. Load the file using selector below.

Drag and drop your file here or

Choose file
*.xlsx (max 20 MB)

4. Click the "Add to quote" button.