Short Name | α-D-Mannopyranose |
Description | Mannan polysaccharide is known as a vaccine adjuvant that mainly binds to mannose receptors and leads to the activation of the complement pathway with enhanced phagocytosis of the antigen. In addition, it also operates via the inflammasome pathway through secretion of IL1b and as a ligand for TLR4. The reduced form of mannan (mannose) is known for the activation of the Th2 pathway when administrated with an antigen, while oxidized mannan in known to activate the Th1 pathway. Mannan coupled with a recombinant protein antigen was shown to enhance higher production of specific IgGs compared with cholera toxin. |
Storage | -20°C |
Form | Solid |
Purity | >98% |
Molecular Formula | C6H12O6 |
Formula Weight | 180.16 g/mol |
CAS No. | 7296-15-3 |
Catalog: CDAD24-013-T
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