Structure | |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis |
Description | Gint4.T aptamer sodium is a nuclease-resistant RNA aptamer-based antagonist targeting platelet-derived growth factor receptor beta (PDGFRβ) (Kd: 9.6 nM). Gint4.T aptamer sodium inhibits PDGFRβ heterodimerization and EGFR transactivation. It can significantly inhibit cell migration and proliferation, induce differentiation and prevent tumor growth in vivo. Gint4.T aptamer sodium specifically inhibits PDGFRβ-mediated tropism of mesenchymal stem cells (MSCs) toward the tumor microenvironment. |
Technology Applications | Cancer |
Catalog: CDAPT24-044-L
Catalog: CDAPT24-045-L
Catalog: CDAPT24-028-L
Catalog: CDAPT24-017-L
Catalog: CDAPT24-055-L
Catalog: CDAPT24-051-L
Catalog: CDAPT24-050-L
Catalog: CDAPT24-091-L
1. Download the template.
2. Enter product information on the template (maximum number of products: 200).
3. Load the file using selector below.
1. Download the template.
2. Enter product information on the template (maximum number of products: 200).
3. Load the file using selector below.