Short Name | Gint4.T aptamer sodium |
Description | Gint4.T aptamer sodium is a nuclease-resistant RNA aptamer-based antagonist targeting platelet-derived growth factor receptor beta (PDGFRβ) (Kd: 9.6 nM). Gint4.T aptamer sodium inhibits PDGFRβ heterodimerization and EGFR transactivation. It can significantly inhibit cell migration and proliferation, induce differentiation and prevent tumor growth in vivo. Gint4.T aptamer sodium specifically inhibits PDGFRβ-mediated tropism of mesenchymal stem cells (MSCs) toward the tumor microenvironment. |
Technology Applications | Cancer |
Structure | |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis |
Affinity & Target | PDGFRβ |
Catalog: CDAPT24-001-L
Catalog: CDAPT24-002-L
Catalog: CDAPT24-003-L
Catalog: CDAPT24-004-L
Catalog: CDAPT24-005-L
Catalog: CDAPT24-006-L
Catalog: CDAPT24-007-L
Catalog: CDAPT24-009-L