Gint4.T aptamer sodium


Gint4.T aptamer sodium

Catalog:CDAPT24-008-L

Unit Size:50 mg, 100 mg, 250 mg

INQUIRY Datasheet

Short Name Gint4.T aptamer sodium
Description Gint4.T aptamer sodium is a nuclease-resistant RNA aptamer-based antagonist targeting platelet-derived growth factor receptor beta (PDGFRβ) (Kd: 9.6 nM). Gint4.T aptamer sodium inhibits PDGFRβ heterodimerization and EGFR transactivation. It can significantly inhibit cell migration and proliferation, induce differentiation and prevent tumor growth in vivo. Gint4.T aptamer sodium specifically inhibits PDGFRβ-mediated tropism of mesenchymal stem cells (MSCs) toward the tumor microenvironment.
Technology Applications Cancer
Structure Gint4.T aptamer sodium
Storage Please store the product under the recommended conditions in the Certificate of Analysis
Affinity & Target PDGFRβ

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