Structure | |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis |
Description | P12FR2 aptamer sodium is a 2''-fluoropyrimidine-modified RNA aptamer targeting human PAUF with an estimated apparent KD of 77 nM. P12FR2 aptamer sodium inhibits PAUF-induced migration of PANC-1 (human pancreatic cancer cells) in wound healing assays and suppresses tumor growth in a mouse CFPAC-1 pancreatic cancer model. |
Technology Applications | Cancer |
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