Structure | |
Purity | >95% |
Storage | Store at 0-4°C |
Molecular Weight | 334.32 |
Molecular Formula | C16H18N2O6 |
CAS No. | 64987-85-5 |
Appearance | White powder |
Description | Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC) is a non-cleavable and membrane permeable crosslinker. It contains an amine-reactive N -hydroxysuccinimide (NHS ester) and a sulfhydryl-reactive maleimide group. NHS esters react with primary amines at pH 7-9 to form stable amide bonds. Maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. |
Solubility | Soluble in DCM, THF, Acetonitrile, DMF and DMSO |
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