Synonym | HO-PLGA-COOH, or α-hydroxyl-ω-carboxyl poly(D,L-lactide-co-glycolide) |
Common Use | HO-PLGA-COOH can be used to prepare biodegradable polymeric nanoparticles, which can be further modified by amine-reactive entities. PLGA has been approved by the US FDA to use in drug delivery systems due to controlled and sustained- release properties, low toxicity, and biocompatibility with tissue and cells. |
Structure | |
Functional Group | Hydroxyl/COOH |
PLGA Molecular Weight | 10,000 Da |
Monomer Ratio | LA:GA 50:50 |
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