Synonym | HO-PLGA-SH, or α-hydroxyl-ω-thiol poly(D,L-lactide-co-glycolide |
Common Use | HO-PLGA-SH can be used to prepare biodegradable polymeric nanoparticles. Thiol, or SH, sulfhydryl, or mercapto group selectively reacts with maleimide, OPSS, vinylsulfone and transition metal surface including gold, silver, etc. PLGA has been approved by the US FDA to use in drug delivery systems due to controlled and sustained- release properties, low toxicity, and biocompatibility with tissue and cells. |
Structure | |
Functional Group | Hydroxyl/Thiol |
PLGA Molecular Weight | 20,000 Da |
Monomer Ratio | LA:GA 50:50 |
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