Common Use | Maleimide-PEG-Hydroxyl (MAL-PEG-OH) is a linear heterobifunctional PEG reagent with a maleimide and a hydroxyl group. It is a useful crosslinking reagent with a PEG spacer. Maleimide reacts with thiol, SH, sulfhydryl or mercapto, and hydroxyl can react with carboxylic acid. MAL-PEG-OH can also be used to synthesize PEGylated block copolymer such as PLA-PEG (poly-L-lactic acid-co-polyethylene glycol) and PCL-PEG (polycaprolactone-co-polyethylene glycol) through hydroxyl initiated polymerization with lactide or caprolactone. Maleimide contains a reactive C=C double bond and is light or oxygen sensitive. |
Structure | |
PEG Molecular Weight | 1,000 Da |
Functional Group | Maleimide/Hydroxyl |
Catalog: CDN1701
Catalog: CDP23-0510
Catalog: CDA-2113
Catalog: CDP23-0853
Catalog: CDN1559
Catalog: CDP23-1018
Catalog: CDBCP409
Catalog: CDPB-2017
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