Common Use | Aldehyde-PEG-Aldehyde (ALD-PEG-ALD) is a linear bifunctional crosslinking PEG reagent with one aldehyde at both ends of PEG. Aldehyde reacts with amine and N-terminal of peptide and protein to form an imine containing a C=N double bond, which can be further reduced to a more stable C-N bond. PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrazone linkage. |
Structure | |
PEG Molecular Weight | 2,000 Da |
Functional Group | Aldehyde |
Catalog: CDA-1025
Catalog: CDP23-0222
Catalog: CDN1886
Catalog: CDN1912
Catalog: CDN1941
Catalog: CDP23-0151
Catalog: CDBCP143
Catalog: CDA-1023
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