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Methoxy poly(ethylene glycol)-Iodolacetyl


Methoxy poly(ethylene glycol)-Iodolacetyl

mPEG-Iodoacetyl

Catalog:CDN2051

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$695

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Common UseMethoxy poly(ethylene glycol)-Iodolacetyl (MPEG-IA) is one type of linear monofunctional PEG acid reagents. PEG-IA can be used to react with thiol groups.Haloacetyl reaction chemistry: The most commonly used haloacetyl crosslinkers contain an iodoacetyl or a bromoacetyl group. Haloacetyls react with sulfhydryl groups at physiologic pH. The reaction of the iodoacetyl group proceeds by nucleophilic substitution of iodine with a sulfur atom from a sulfhydryl group, resulting in a stable thioether linkage.
Structure Methoxy poly(ethylene glycol)-Iodolacetyl
PEG Molecular Weight5,000 Da
Functional GroupMethoxy/Iodoacetyl
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