Methoxy poly(ethylene glycol)-Iodolacetyl
mPEG-Iodoacetyl
Catalog:CDN2053
Common Use | Methoxy poly(ethylene glycol)-Iodolacetyl (MPEG-IA) is one type of linear monofunctional PEG acid reagents. PEG-IA can be used to react with thiol groups.Haloacetyl reaction chemistry: The most commonly used haloacetyl crosslinkers contain an iodoacetyl or a bromoacetyl group. Haloacetyls react with sulfhydryl groups at physiologic pH. The reaction of the iodoacetyl group proceeds by nucleophilic substitution of iodine with a sulfur atom from a sulfhydryl group, resulting in a stable thioether linkage. |
Structure | |
PEG Molecular Weight | 20,000 Da |
Functional Group | Methoxy/Iodoacetyl |
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