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1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol methoxy


1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol methoxy

DOPE-mPEG

Catalog:CDN2135

Unit Size
Price
$695

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Common Use1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol methoxy (DOPE-MPEG) is a linear heterobifunctional PEGylation reagent with an unsaturated DOPE phospholipid. It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an amine group for bioconjugation. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the amine group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide.
Structure 1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol methoxy
PEG Molecular Weight5,000 Da
Functional GroupDOPE/Methoxy
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