Common Use | 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated polyethylene glycol with active succinimidyl ester (DSPE-PEG-NHS) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and an active ester group. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a NHS group for conjugation with amine-containing moieties or ligands. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. |
Structure | |
PEG Molecular Weight | 3,400 Da |
Functional Group | DSPE/NHS |
Catalog: CDP23-0647
Catalog: CDPB-3004
Catalog: CDN2277
Catalog: CDP23-0310
Catalog: CDP23-0961
Catalog: CDP23-0140
Catalog: CDP23-0902
Catalog: CDN2226
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