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1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-PEG-NHS


1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-PEG-NHS

DSPE-PEG-NHS

Catalog:CDN2270

Unit Size
Price
$695

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Common Use1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated polyethylene glycol with active succinimidyl ester (DSPE-PEG-NHS) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and an active ester group. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a NHS group for conjugation with amine-containing moieties or ligands. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide.
Structure 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-PEG-NHS
PEG Molecular Weight5,000 Da
Functional GroupDSPE/NHS
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