Common Use | DSPE-PEG-SH is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a thiol group. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a thiol group for conjugation with thiol-containing molecules. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. |
Structure | |
PEG Molecular Weight | 3,400 Da |
Functional Group | DSPE/Thiol |
Catalog: CDN2287
Catalog: CDP23-0143
Catalog: CDN2236
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Catalog: CDA-3011
Catalog: CDN2250
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