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1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-PEG-Vinylsulfone


1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-PEG-Vinylsulfone

DSPE-PEG-VS

Catalog:CDN2289

Unit Size
Price
$920

Buy Now Need technical support? Datasheet

Common UseDSPE-PEG-Vinylsulfone (DSPE-PEG-VS) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a biotin. It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle which has functional vinylsulfone on the surface that can react with thiol-containing peptides or antibodies. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the VS group to bind to targeting molecules including antibody, aptamer, protein, and peptide.
Structure 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-PEG-Vinylsulfone
PEG Molecular Weight3,400 Da
Functional GroupDSPE/Vinylsulfone
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