Common Use | Ald-CH2-PEG3-Azide is a crosslinker containing an azide group and an aldehyde group. The azide group enables PEGylation via Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. The aldehyde group reacts with amines and the N-terminal of peptides and proteins to form an imine containing a C=N double bond, which can be further reduced. PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage. |
Structure | |
PEG Molecular Weight | 217.2 g/mol |
Functional Group | Aldehyde/Azide |
Purity | 98% |
Storage | -20°C |
Molecular Formula | C8H15N3O4 |
CAS No. | 1002342-83-7 |
Catalog: CDPB-04162
Catalog: CDPB-04185
Catalog: CDPB-041216
Catalog: CDPB-041561
Catalog: CDP23-0719
Catalog: CDPB-041023
Catalog: CDPB-041002
Catalog: CDN-04012
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