Common Use | Linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility. |
Structure | |
PEG Molecular Weight | 618.7 g/mol |
Functional Group | Maleimide/Hydroxyl |
Purity | 95% |
Storage | -20°C |
Molecular Formula | C29H42N6O9 |
CAS No. | 2055041-38-6 |
Catalog: CDPB-04662
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