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MAL-PEG2-Val-Cit-PAB-OH


MAL-PEG2-Val-Cit-PAB-OH

Catalog:CDPB-041348

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INQUIRY Datasheet

Common UseLinker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.
Structure MAL-PEG2-Val-Cit-PAB-OH
PEG Molecular Weight618.7 g/mol
Functional GroupMaleimide/Hydroxyl
Purity95%
Storage-20°C
Molecular FormulaC29H42N6O9
CAS No.2055041-38-6
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