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MAL-PEG4-Val-Cit-PAB-PNP


MAL-PEG4-Val-Cit-PAB-PNP

Catalog:CDPB-041350

INQUIRY Datasheet

Common UseLinker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.
Structure MAL-PEG4-Val-Cit-PAB-PNP
PEG Molecular Weight871.9 g/mol
Functional GroupMaleimide/PNP
Purity97%
Storage-20°C
Molecular FormulaC40H53N7O15
CAS No.2112738-09-5
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